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Record #404 on
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Zhelnov P. A critical appraisal of ‘Musillo C, Borgi M, Saul N, Möller S, Luyten W, Berry A, Cirulli F. Natural products improve healthspan in aged mice and rats: a systematic review and meta- analyses. Neurosci Biobehav Rev. 2020 Dec 9:S0149-7634(20)30674-6. doi: 10.1016/j.neubiorev.2020.12.001. Epub ahead of print. PMID: 33309907’. Zheln. 2020 Dec 19;51(2):r404d15. URI:

Zheln Review Appraisal in 10 Steps:

  1. ✅ Downloaded from the PubMed Systematic Subset Daily Updates
  2. 🔄 Meets Shojania & Bero 2001 True Positive Criteria for Systematic Reviews by Either Title or Abstract?
  3. 🔄 Full Text or Other Reports Collected by Zheln
  4. 🔄 Generates Pragmatic Evidence Directly Relevant to Evidence-Based Practice?
  5. 🔄 Is Duplicate?
  6. 🔄 Passed or Failed Replication?
  7. 🔄 Has Critical Conduct Flaws?
  8. 🔄 Liked or Disliked by Zheln?
  9. 🔄 Practical Implications Summarized by Zheln
  10. 🔄 Appraisal Published & Call for Crowdfunding

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