Probiotics for the Prevention of Antibiotic-Associated Diarrhea

Zhelnov P. A critical appraisal of ‘Liao W, Chen C, Wen T, Zhao Q. Probiotics for the Prevention of Antibiotic- associated Diarrhea in Adults: A Meta-Analysis of Randomized Placebo-Controlled Trials. J Clin Gastroenterol. 2020 Nov 23. doi: 10.1097/MCG.0000000000001464. Epub ahead of print. PMID: 33234881’. Zheln. 2020 Nov 28;48(2):r139d25. URI: https://zheln.com/record/2020/11/25/139/.

Zheln Review Appraisal in 10 Steps:

1. ✅ Downloaded from the PubMed Systematic Subset Daily Updates
2. ✅ Meets Shojania & Bero 2001 True Positive Criteria for Systematic Reviews by Title
3. ✅ Full Text Collected by Zheln
4. ✅ Generates Pragmatic Evidence Directly Relevant to Evidence-Based Practice
5. ❌ Is Duplicate
6. 🔄 Passed or Failed Replication?
7. 🔄 Has Critical Conduct Flaws?
8. 🔄 Liked or Disliked by Zheln?
9. 🔄 Practical Implications Summarized by Zheln
10. 🔄 Appraisal Published & Call for Crowdfunding

Very similar to this one:

https://journals.sagepub.com/doi/full/10.1177/2050640617736987

Also similar to this one although the latter is about outpatients only:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745464/

Found these links using a superficial Google search only; thus, the study is at least partly duplicate.

I have already started appraisal of this article and have found there is evidence that this study is duplicate research. Therefore, assessing comprehensively the problem in question will not be limited to assessing this study only and will take considerable time and effort. I will complete the appraisal as soon as I’m able to. Please return sometime later or follow the progress of this page here or on GitHub as I do the appraisal. Also, you can look for similar systematic review appraisals using search or by tapping on AMA specialty tags at the bottom of this page or in the side menu.

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