Record Awaiting Appraisal

Zhelnov P. A critical appraisal of ‘Chua XY, Ho LTY, Xiang P, Chew WS, Lam BWS, Chen CP, Ong WY, Lai MKP, Herr DR. Preclinical and Clinical Evidence for the Involvement of Sphingosine 1-Phosphate Signaling in the Pathophysiology of Vascular Cognitive Impairment. Neuromolecular Med. 2020 Nov 12. doi: 10.1007/s12017-020-08632-0. Epub ahead of print. PMID: 33180310’. Zheln. 2020 Nov 14;46(2):r92d12. URI: https://zheln.com/record/2020/11/12/92/.

Zheln Review Appraisal in 10 Steps:

1. ✅ Downloaded from the PubMed Systematic Subset Daily Updates
2. 🔄 Meets Shojania & Bero 2001 True Positive Criteria for Systematic Reviews by Either Title or Abstract?
3. 🔄 Full Text or Other Reports Collected by Zheln
4. 🔄 Generates Pragmatic Evidence Directly Relevant to Evidence-Based Practice?
5. 🔄 Is Duplicate?
6. 🔄 Passed or Failed Replication?
7. 🔄 Has Critical Conduct Flaws?
8. 🔄 Liked or Disliked by Zheln?
9. 🔄 Practical Implications Summarized by Zheln
10. 🔄 Appraisal Published & Call for Crowdfunding

I have uploaded this record from PubMed but haven’t appraised it yet.

If you want me to appraise this record, I’ve got several options for you:

• Wait until I get my hands on it myself.
• Buy a subscription on Patreon, GitHub Sponsors, or Open Collective for $1 to $600 and PM me with the review request.
• Send me $1 via PayPal with this reference in the message, and I’ll happily appraise it for you.
• Contact me by email or on Twitter, Facebook, Instagram, or Telegram, and I’m sure we’ll find a way around.