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Zhelnov P. A critical appraisal of ‘Sáez ME, González-Pérez A, Hernández-Olasagarre B, Beà A, Moreno-Grau S, de Rojas I, Monté-Rubio G, Orellana A, Valero S, Comella JX, Sanchís D, Ruiz A. Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer’s disease. Sci Rep. 2019 Nov 13;9(1):16665. doi: 10.1038/s41598-019-52724-2. PMID: 31723151; PMCID: PMC6853976’. Zheln. 2020 Nov 14;46(2):r698d12. URI: https://zheln.com/record/2020/11/12/698/.

Zheln Review Appraisal in 10 Steps:

  1. ✅ Downloaded from the PubMed Systematic Subset Daily Updates
  2. 🔄 Meets Shojania & Bero 2001 True Positive Criteria for Systematic Reviews by Either Title or Abstract?
  3. 🔄 Full Text or Other Reports Collected by Zheln
  4. 🔄 Generates Pragmatic Evidence Directly Relevant to Evidence-Based Practice?
  5. 🔄 Is Duplicate?
  6. 🔄 Passed or Failed Replication?
  7. 🔄 Has Critical Conduct Flaws?
  8. 🔄 Liked or Disliked by Zheln?
  9. 🔄 Practical Implications Summarized by Zheln
  10. 🔄 Appraisal Published & Call for Crowdfunding

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