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Record #66 on
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Zhelnov P. A critical appraisal of ‘Dhuyvetter D, Tekle F, Nazarov M, Vreeken RJ, Borghys H, Rombouts F, Lenaerts I, Bottelbergs A. Direct nose to brain delivery of small molecules: critical analysis of data from a standardized in vivo screening model in rats. Drug Deliv. 2020 Dec;27(1):1597-1607. doi: 10.1080/10717544.2020.1837291. PMID: 33169635’. Zheln. 2020 Nov 14;46(2):r66d10. URI: https://zheln.com/record/2020/11/10/66/.

Zheln Review Appraisal in 10 Steps:

  1. ✅ Downloaded from the PubMed Systematic Subset Daily Updates
  2. 🔄 Meets Shojania & Bero 2001 True Positive Criteria for Systematic Reviews by Either Title or Abstract?
  3. 🔄 Full Text or Other Reports Collected by Zheln
  4. 🔄 Generates Pragmatic Evidence Directly Relevant to Evidence-Based Practice?
  5. 🔄 Is Duplicate?
  6. 🔄 Passed or Failed Replication?
  7. 🔄 Has Critical Conduct Flaws?
  8. 🔄 Liked or Disliked by Zheln?
  9. 🔄 Practical Implications Summarized by Zheln
  10. 🔄 Appraisal Published & Call for Crowdfunding

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